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新冠新毒株KP.2在美英等多国迅速传播,或更具传染性_我的网站

人民的名义

一 |     

根据美国疾病控制与预防中心(CDC)近期更新的数据,如今在美传播的主要变体是以KP.2为首的“FLiRT”一族:KP.2的占比已经达到25%。    
Air China flight CA723 takes off from the Beijing Capital International Airport in Beijing, on August 12, 2026. China launched the first international route featuring its homegrown C919 aircraft, connecting Beijing with Ulaanbaatar, capital of Mongolia. Photo: VCG
    Air China flight CA723 takes off from the Beijing Capital International Airport in Beijing, on August 12, 2026. China launched the first international route featuring its homegrown C919 aircraft, connecting Beijing with Ulaanbaatar, capital of Mongolia. Photo: VCGAt around 4:58 pm on Wednesday, Air China flight CA723, a China-designed and manufactured C919 aircraft carrying 121 passengers, landed in Mongolian capital Ulaanbaatar, marking the latest milestone in the C919's commercial operation since its maiden commercial flight on May 28, 2023. The journey, which started in Beijing, was more than another takeoff, as it marked the C919's first international commercial flight and the beginning of regular international operations for China's homegrown large passenger aircraft.
As the C919 climbs higher and flies farther beyond China's borders, the runway behind it gradually disappears. What comes into focus instead is a much broader journey - one in which China's advanced engineering capabilities are reaching new markets, new partners and new possibilities around the world.
Historic moment
Hours before takeoff, a passenger surnamed Zhang, who was completing check-in procedures at Beijing Capital International Airport, said with a smile that he had stumbled into a "historic moment" by chance.
"I didn't pay much attention when I booked the ticket. I had heard that our homegrown C919 would soon begin international service, but I never expected it would be this very flight," Zhang told the Global Times on Wednesday. "I feel incredibly proud and excited."
From its maiden flight in Shanghai in 2017, when its first takeoff had many watching with bated breath, to its first scheduled international commercial service today, the C919's journey reflects China's sustained push to build up its capabilities in advanced aviation manufacturing. 
In recent years, China's top-level policies have strongly supported the development of high-end manufacturing. As the nation enters the opening year of the 15th Five-Year Plan period (2026-30), Chinese high-end manufacturing is increasingly translating technological breakthroughs into globally competitive products and solutions to contribute more broadly to industrial development and connectivity worldwide, Chinese experts noted.
And the C919 program is one of China's most ambitious endeavors to push the frontiers of high-end manufacturing.
The C919 is China's first self-developed trunk jetliner in accordance with international airworthiness standards and registered with independent intellectual property rights, according to the Xinhua News Agency on Wednesday.
Industry experts said the C919's progress reflects the rapid advance of China's broader manufacturing capabilities. Only a handful of countries are capable of developing single-aisle mainline passenger jets, and even fewer can bring a certified aircraft into commercial service.
The C919 aircraft's biggest achievement is that China has built the capability to take a large passenger jet from the drawing board all the way to a certified commercial product, covering overall design, airframe manufacturing, system integration and airworthiness approval, Wang Ya'nan, editor-in-chief of Beijing-based Aerospace Knowledge magazine, told the Global Times on Wednesday.
Much of the aircraft's design, major structural manufacturing and key systems are completed in China. He said this marks a significant step forward in China's civil aviation manufacturing capability, placing the country among the few able to develop a modern trunk-line jet and bring it into commercial service. Its expanding operations now represent the next stage of that progress, he added.
As of Monday, the C919 aircraft had served 57 routes linking 25 cities and handled more than 7.5 million passenger trips, said the Commercial Aircraft Corporation of China (Comac), the jet developer, according to Xinhua.
However, the C919 still faces intense competition in a global market dominated by established players. Experts said, however, that its competitiveness could continue to strengthen as operational experience grows and China accelerates indigenous development of key components and systems.
The UK-based aviation industry publication Airline Economics noted on July 13 that Malaysia Airlines continues to consider Comac's C919 as a future fleet option, but Western regulatory certification remains a key requirement before the carrier would consider operating the Chinese narrowbody.
This has also brought into sharper focus the dual considerations of certification and market demand among potential international customers for the C919, as Wang said this is precisely why the C919's continued expansion into new routes and markets matters. 
As cross-border services expand, the C919 will also need to move closer to international operating standards by building a support network that goes beyond its domestic maintenance system to cover the full cycle of international operations, including regulatory coordination, overseas maintenance facilities and spare-parts logistics, Han Tao, an expert with China's civil aviation think tank, told the Global Times on Wednesday. 
Strengthening these capabilities will be crucial to supporting more international routes and meeting the standards and operational needs of potential overseas customers, Han said.
Meanwhile, industry observers noted that China is also stepping up efforts to advance key components and systems for large commercial aircraft, an area that remains a major challenge for most countries' aviation industries, with mature capabilities still largely concentrated in the US, the UK and France.
Pushing boundaries, sharing opportunities
As the C919 flies farther, it is carrying with it not only China's advances in high-end manufacturing, but a broader story of how Chinese innovation is moving from breakthroughs at home to new possibilities shared with the world.
Underpinning that shift is China's expanding advanced manufacturing capacity and increasingly complete industrial ecosystem, which are helping turn technological breakthroughs into scalable products, a Chinese expert said.
China is upgrading its traditional industrial base while cultivating new sectors that could shape future competitiveness, seeking to move beyond scale and cost advantages toward a more innovation-driven industrial model, injecting new impetus into the country's high-quality development, according to Xinhua's another report on July 21.
The nation's 15th Five-Year Plan underscores the development of a modernized industrial system with advanced manufacturing as its backbone, the report said.
China's vast and diverse market provides advanced manufacturing with something equally important as technological capability: abundant real-world scenarios for testing, refinement and commercialization, Bian Yongzu, executive deputy editor-in-chief of Modernization of Management magazine.
This helps turn breakthroughs into mature, scalable products more quickly. Over the longer term, he said, advanced manufacturing will strengthen China's competitiveness by combining stronger industrial capabilities with complete supply chains and global cooperation, allowing more Chinese technologies, products and solutions to reach international markets, Bian said.
Aviation manufacturing, as a key pillar of high-end manufacturing, is benefiting from this broader push toward industrial upgrading and technological innovation.
At the fourth China International Supply Chain Expo held in Beijing in June, a complete aviation industry innovation chain stands out, spanning aviation materials, core forgings and low-altitude economy applications, drawing widespread attention to the participating companies, Xinhua reported.
Bian said that a complex project such as the C919 can drive coordinated upgrades across advanced materials, precision equipment, core components, system integration, logistics and skilled talent. In this sense, building a large commercial aircraft is a comprehensive test of a country's industrial depth, supply-chain coordination, and ability to turn sophisticated technologies into reliable commercial products.
值得注意的是,新冠病毒的新变种KP.2正在加拿大、英国等多个国家迅速传播。今年5月初,世界卫生组织已将KP.2亚变种列为监测中变异株。世界卫生组织表示,将继续密切监测病毒的演变。
美国疾控中心最新数据显示,目前,KP.2占美国感染病例的四分之一以上。截至5月11日的两周内,KP.2估计占美国病例的28.2%,高于4月中旬的约6%和3月中旬的仅1%。
据悉,KP.2是JN.1变种的后代,有时被称为“FLiRT”变体,因其在刺突蛋白中的突变位置而得名。包括KP.1.1在内的其他FLiRT变种也在美国流行,但还没有KP.2那么普遍。

二 | “FLiRT”最初是在美国下水道系统中发现的,但确切来源尚不清楚。

这意味着,新冠病毒仍在变异。CDC发言人发出警告称,病毒通过突变不断发生变化,有时这些突变会导致病毒产生新的变种。一些变化和突变使病毒更容易传播或使其对治疗或疫苗产生抵抗力。

三 | 随着病毒的传播,它可能会发生变化并且变得更难以阻止。

当前,CDC正在监测KP.2和KP.1.1引起的感染。早期数据表明,它们产生与JN.1相似的症状,通常出现在感染后2至14天,这些症状主要影响上呼吸道,包括喉咙痛、鼻塞、流鼻涕、咳嗽、发烧、头痛以及味觉和嗅觉丧失。

四 |

美国传染病专家罗伯特·墨菲博士表示,虽然症状和严重程度似乎与之前的新冠病毒毒株大致相同,但新变种似乎更具传染性。墨菲敦促公众了解新冠疫苗注射的最新情况,特别是那些因该病毒而出现严重并发症的风险较高的人。虽然大多数人对疫苗接种或以前感染过的新冠病毒有一定的免疫力,但墨菲指出,“对于新冠病毒感染(COVID-19),免疫力会随着时间的推移而减弱。”
到目前为止,这一变体尚未被证明会导致更严重的疾病,疫苗也仍然有效。
英国华威大学病毒学家、分子肿瘤学教授Lawrence Young表示,“我们担心这个KP.2会在夏天引起一波感染。早期证据表明,KP.2似乎比以前的亚株更具传染性,但现在判断它是否更危险还为时过早。我们应该监测这个亚谱系的传播,但鉴于现在没有很多测试,这很困难。”
值得注意的是,新冠病毒的新变体FLiRT正在加拿大、英国等国家迅速传播。
当地时间5月9日,据Global News报道,KP.2迅速在加拿大占据主导地位,截至4月28日,全国数据显示,KP.2占加拿大所有COVID-19病例的26.6%,超过其他JN.1亚变种。
同时,FLiRT变体在英国似乎也逐渐占据主导地位。

五 | Cov Spectrum的数据表明,KP.2和KP.1.1的组合占英国病例的40%。英国卫生安全局(UKHSA)尚未对FLiRT发表评论,但英国病例的增加可能表明它是新的主要变种。

今年5月初,世界卫生组织(WHO)已将KP.2亚变种列为监测中变异株。世卫组织COVID-19技术负责人Maria Van Kerkhove此前表示,“KP.2是JN.1的后代谱系,而JN.1是全球主要菌株,KP.2刺突蛋白有额外的突变。

六 | 还有其他新兴变体,JN.1不断发展,我们将继续看到这些变体传播。”

不过,截至目前,中国国内尚无该毒株传播的迹象。

七 | 据中国疾控中心公布的最新数据,2024年4月1日-4月30日,31个省(自治区、直辖市)及新疆生产建设兵团共报送11299例本土病例新冠病毒基因组有效序列,均为奥密克戎变异株。主要流行株为JN.1系列变异株,占比前三位的分别为JN.1、JN.1.4和JN.1.16。

(羊城晚报•羊城派综合红星新闻、财联社、中疾控官网等)

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Published on:02:20:02


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